PUBLICATIONS
Safety and efficacy of 90Y-FAPI-46 radioligand therapy in patients with advanced sarcoma and other cancer entities
Wolfgang P Fendler, Kim M Pabst, Lukas Kessler, Pedro Fragoso Costa, Justin Ferdinandus, Manuel Weber, Maria Lippert, Katharina Lueckerath, Lale Umutlu, Karina Kostbade, Ilektra A Mavroeidi, Martin Schuler, Marit Ahrens, Christoph Rischpler, Sebastian Bauer, Ken Herrmann, Jens T Siveke, Rainer Hamacher Abstract Purpose: We [...]
Pitfalls and Common Findings in 68 Ga-FAPI PET: A Pictorial Analysis
Lukas Kessler, Justin Ferdinandus, Nader Hirmas, Fadi Zarrad, Michael Nader, David Kersting, Manuel Weber, Sandra Kazek, Miriam Sraieb, Rainer Hamacher, Katharina Lueckerath, Lale Umutlu, Wolfgang P Fendler, Christoph Rischpler Abstract: Fibroblast activation protein inhibitor (FAPI) PET/CT is a new tool in the diagnostic workup of [...]
Comparison of 68 Ga-FAPI PET/CT and 18 FDG PET/CT Modalities in Gastrointestinal System Malignancies with Peritoneal Involvement
Umut Elboga, Ertan Sahin, Tulay Kus, Yusuf Burak Cayirli, Gokmen Aktas, Merve Okuyan, Havva Yesil Cinkir, Fatih Teker, Ozlem Nuray Sever, Alper Aytekin, Latif Yılmaz, Aydın Aytekin, Ufuk Cimen, Vuslat Mumcu, Benan Kilbas, Kurtulus Eryilmaz, Davut Cakici, Yusuf Zeki Celen Purpose: In this study, we [...]
FAPI-PET Opens a New Window for Understanding of Immune-Mediated Inflammatory Diseases
Torsten Kuwert, Christian Schmidkonz, Olaf Prante, Georg Schett, Andreas Ramming Abstract: In vivo visualization of inflammatory lesions in the body has been revolutionized by positron emission tomography (PET) with F-18-deoxyglucose (FDG) as a tracer and by magnetic resonance imaging (MRI) with gadolinium-labelled contrast media. Apart [...]
Comparison of 68 Ga-FAPI and 18 F-FDG PET/CT in the Evaluation of Advanced Lung Cancer
Lijuan Wang, Ganghua Tang, Kongzhen Hu, Xinran Liu, Wenlan Zhou, Hongsheng Li, Shun Huang, Yanjiang Han, Li Chen, Jinmei Zhong, Hubing WuAbstract:Background Gallium 68 (68Ga)-labeled fibroblast-activation protein inhibitor (FAPI) has recently been introduced as a promising tumor imaging agent. Purpose To compare 68Ga-FAPI PET/CT with fluorine [...]
Head-to-head Intra-individual Comparison of [ 68 Ga]-FAPI and [ 18 F]-FDG PET/CT in Patients with Bladder Cancer
E Novruzov, K Dendl, H Ndlovu, P L Choyke, M Dabir, M Beu, F Novruzov, E Mehdi, F Guliyev, S A Koerber, I Lawal, G Niegisch, J Debus, U Haberkorn, M Sathekge, F L Giesel Aim/purpose: Fibroblast activation protein-(FAP)-ligands, a novel class of tracers for [...]
Feasibility of [ 68 Ga]Ga-FAPI-46 PET/CT for detection of nodal and hematogenous spread in high-grade urothelial carcinoma
Lena M Unterrainer, Simon Lindner, Lennert Eismann, Jozefina Casuscelli, Franz-Josef Gildehaus, Vinh Ngoc Bui, Nathalie L Albert, Adrien Holzgreve, Leonie Beyer, Andrei Todica, Matthias Brendel, Clemens C Cyran, Alexander Karl, Christian G Stief, Stephan T Ledderose, Marcus Unterrainer, Peter Bartenstein, Vera Wenter, Alexander Kretschmer [...]
Could Fibroblast Activation Protein (FAP)-Specific Radioligands Be Considered as Pan-Tumor Agents?
Chiara Da Pieve, Marta Costa Braga, David R Turton, Frank A Valla, Pinar Cakmak, Karl-Heinz Plate, Gabriela Kramer-Marek Abstract: Cancer-associated fibroblasts (CAFs) can strongly modulate the response to therapy of malignant tumor cells, facilitating their continuous proliferation and invading behaviors. In this context, several [...]
New Fully Automated Preparation of High Apparent Molar Activity 68 Ga-FAPI-46 on a Trasis AiO Platform
Chiara Da Pieve, Marta Costa Braga, David R Turton, Frank A Valla, Pinar Cakmak, Karl-Heinz Plate, Gabriela Kramer-Marek Abstract:A large number of applications for fibroblast activation protein inhibitors (FAPI)-based PET agents have been evaluated in conditions ranging from cancer to non-malignant diseases such as [...]
Fibroblast activation protein-based theranostics in cancer research: A state-of-the-art review
Liang Zhao, Jianhao Chen, Yizhen Pang, Kaili Fu, Qihang Shang, Hua Wu, Long Sun, Qin Lin, Haojun Chen Abstract: In recent years, quinoline-based fibroblast activation protein (FAP) inhibitors (FAPI) have shown promising results in the diagnosis of cancer and several other diseases, making them [...]