Publications
Head-to-head Intra-individual Comparison of [ 68 Ga]-FAPI and [ 18 F]-FDG PET/CT in Patients with Bladder Cancer
E Novruzov, K Dendl, H Ndlovu, P L Choyke, M Dabir, M Beu, F Novruzov, E Mehdi, F Guliyev, S A Koerber, I Lawal, G Niegisch, J Debus, U Haberkorn, M Sathekge, F L Giesel Aim/purpose: Fibroblast activation protein-(FAP)-ligands, a novel class of tracers for [...]
Feasibility of [ 68 Ga]Ga-FAPI-46 PET/CT for detection of nodal and hematogenous spread in high-grade urothelial carcinoma
Lena M Unterrainer, Simon Lindner, Lennert Eismann, Jozefina Casuscelli, Franz-Josef Gildehaus, Vinh Ngoc Bui, Nathalie L Albert, Adrien Holzgreve, Leonie Beyer, Andrei Todica, Matthias Brendel, Clemens C Cyran, Alexander Karl, Christian G Stief, Stephan T Ledderose, Marcus Unterrainer, Peter Bartenstein, Vera Wenter, Alexander Kretschmer [...]
Could Fibroblast Activation Protein (FAP)-Specific Radioligands Be Considered as Pan-Tumor Agents?
Chiara Da Pieve, Marta Costa Braga, David R Turton, Frank A Valla, Pinar Cakmak, Karl-Heinz Plate, Gabriela Kramer-Marek Abstract: Cancer-associated fibroblasts (CAFs) can strongly modulate the response to therapy of malignant tumor cells, facilitating their continuous proliferation and invading behaviors. In this context, several [...]
New Fully Automated Preparation of High Apparent Molar Activity 68 Ga-FAPI-46 on a Trasis AiO Platform
Chiara Da Pieve, Marta Costa Braga, David R Turton, Frank A Valla, Pinar Cakmak, Karl-Heinz Plate, Gabriela Kramer-Marek Abstract:A large number of applications for fibroblast activation protein inhibitors (FAPI)-based PET agents have been evaluated in conditions ranging from cancer to non-malignant diseases such as [...]
Fibroblast activation protein-based theranostics in cancer research: A state-of-the-art review
Liang Zhao, Jianhao Chen, Yizhen Pang, Kaili Fu, Qihang Shang, Hua Wu, Long Sun, Qin Lin, Haojun Chen Abstract: In recent years, quinoline-based fibroblast activation protein (FAP) inhibitors (FAPI) have shown promising results in the diagnosis of cancer and several other diseases, making them [...]
FAP and FAPI-PET/CT in Malignant and Non-Malignant Diseases: A Perfect Symbiosis?
Katharina Dendl 1,2 Stefan A. Koerber 3,4,5 Clemens Kratochwil 1 Jens Cardinale 1,2 Rebecca Finck 1 Mardjan Dabir 2 Emil Novruzov 2Tadashi Watabe 6 Vasko Kramer 7,8 Peter L. Choyke 9 Uwe Haberkorn 1,10,11 and Frederik L. Giesel 1,2 Abstract:A fibroblast activation protein (FAP) [...]