Publications
![FAP Expression in Renal Tumors Assessed by [68Ga]Ga-FAPI-46 PET Imaging and FAP Immunohistochemistry: A Case Series of Six Patients from the Prospective Exploratory Trial NCT04147494](https://sofie.com/wp-content/uploads/2025/12/info.ibamolecular-scaled.jpg)
FAP Expression in Renal Tumors Assessed by [68Ga]Ga-FAPI-46 PET Imaging and FAP Immunohistochemistry: A Case Series of Six Patients
Adrien Holzgreve, Lena M Unterrainer, Kimberly Flores, Ethan C Lam, Christine E Mona, Johannes Czernin, Brian M Shuch, Anthony E Sisk Jr, Jeremie Calais Abstract: Fibroblast activation protein (FAP) has been proposed as a pan-tumor target for PET imaging using FAP-targeted tracers. Here, we [...]
68Ga-FAPI PET/CT Prevents Futile Surgery and Demonstrates Tumor Biology in Patients with Pancreatic Ductal Adenocarcinoma
William McGahan, Alexa Chadwick, Karen Lindsay, Brook Gulhane, Melissa J Latter, Thomas O'Rourke, Paul A Thomas, David Cavallucci Abstract: PET/CT using 68Ga-labeled fibroblast activation protein inhibitor (68Ga-FAPI) may detect occult metastases and identify aggressive tumor biology in patients with pancreatic ductal adenocarcinoma (PDAC). We evaluated [...]
Revealing the hidden: A systematic review and meta-analysis of FAPI-based tracers imaging for brain metastatic lesions
Sajjad Sadeghpour, Atena Aghaee, Hojjat Ahmadzadehfar, Alessio Rizzo, Giorgio Treglia, Ramin Sadeghi Abstract: Background: Regarding the assessment of brain metastatic lesions, [18F]FDG PET/CT encounters challenges due to heightened physiological uptake in normal brain tissue, resulting in poor tumor-to-background ratios (TBR). Detecting brain metastases accurately has [...]
![[68Ga]Ga-FAPI-46 PET accuracy for cancer imaging with histopathology validation: a single-centre, single-arm, interventional, phase 2 trial](https://sofie.com/wp-content/uploads/2025/09/image.png)
[68Ga]Ga-API-46 PET accuracy for cancer imaging with histopathology validation: a single-centre, single-arm, interventional, phase 2 trial
Kim M Pabst, Manuel M Weber, Christina Laschinsky, Patrick Sandach, Timo Bartel, Alina T Küper, Lukas Kessler, Marija Trajkovic-Arsic, Markus Eckstein, Elena Gilman, Michael Nader, Francesco Barbato, Lars E Podleska, Boris A Hadaschik, Rainer Hamacher, David Kersting, Nicola von Ostau, Bastian von Tresckow, Hans-Peter [...]
90 Y-FAPI-46 Theranostics Leads to Near-Complete Metabolic Response in 3 Patients with Solitary Fibrous Tumors
Helena Lanzafame, Christoph E Heilig, Eva Wardelmann, Mélanie Desaulniers, Kim Magaly Pabst, Ilektra Antonia Mavroeidi, Ina Pretzell, Pedro Fragoso Costa, Micheal Nader, Stephan Leyser, Martin Schuler, Sebastian Bauer, Jens Thomas Siveke, Leila Kamkar, Simon Kreutzfeldt, Stefan Fröhling, Sebastian Mühl, Ken Herrmann, Wolfgang Peter Fendler, [...]
Early image acquisition 68Ga-FAPI-46-PET/CT in prone position is promising in the workup of rectosigmoid and anal carcinoma
D Ufton, J Heilinger, H Weis, T Fischer, K Schomäcker, C Bruns, G Dieplinger, H Dapper, E Fokas, C Kobe, A Drzezga, S Ferdinandus, K S Roth Abstract: Purpose: To overcome difficulties with regard to anatomic discrimination of intrapelvic tumors and non-specific intrapelvic uptake (i.e. [...]