Publications
Spatial FAP Expression as Detected by 68 Ga-FAPI-46 Identifies Myofibroblasts Beyond the Infarct Scar After Reperfusion
Annika Hess, Alexandra Renko, Andreas Schäfer, Mira Jung, Daniela Fraccarollo, Jan D Schmitto, Johanna Diekmann, Thomas Thum, Frank M Bengel, Johann Bauersachs, James T Thackeray, Jochen Tillmanns Abstract: Purpose: Myocardial infarction (MI) triggers complex cellular responses essential for tissue repair and remodeling, including myofibroblast [...]
Head-to-head comparison of 18F-FDG and 68Ga-FAPI PET/CT in common gynecological malignancies
Tengfei Li, Jintao Zhang, Yuanzhuo Yan, Yue Zhang, Wenjie Pei, Qingchu Hua, Yue Chen Abstract: Background: 68Ga-FAPI (fibroblast activation protein inhibitor) is a novel and highly promising radiotracer for PET/CT imaging. It has shown significant tumor uptake and high sensitivity in lesion detection across [...]
Discrimination between Inflammatory and Fibrotic Activity in Crohn’s Disease-Associated Ileal-Colonic Anastomotic Strictures by Combined Ga-68-FAPI-46 and F-18-FDG-PET/CT Imaging GalleryDiscrimination between Inflammatory and Fibrotic Activity in Crohn’s Disease-Associated Ileal-Colonic Anastomotic Strictures by Combined Ga-68-FAPI-46 and F-18-FDG-PET/CT Imaging
Discrimination between Inflammatory and Fibrotic Activity in Crohn’s Disease-Associated Ileal-Colonic Anastomotic Strictures by Combined Ga-68-FAPI-46 and F-18-FDG-PET/CT Imaging
Michael Beck, Torsten Kuwert, Armin Atzinger, Maximilian Gerner, Arndt Hartmann, Marc Saake, Michael Uder, Markus Friedrich Neurath, Raja Atreya Abstract: Introduction: The development of an intestinal stricture in patients with Crohn's disease represents an important and frequent complication, reflecting the progressive nature of the disease. [...]
Feasibility, Tolerability, and Preliminary Clinical Response of Fractionated Radiopharmaceutical Therapy with 213Bi-FAPI-46: Pilot Experience in Patients with End-Stage, Progressive Metastatic Tumors GalleryFeasibility, Tolerability, and Preliminary Clinical Response of Fractionated Radiopharmaceutical Therapy with 213Bi-FAPI-46: Pilot Experience in Patients with End-Stage, Progressive Metastatic Tumors
Feasibility, Tolerability, and Preliminary Clinical Response of Fractionated Radiopharmaceutical Therapy with 213Bi-FAPI-46: Pilot Experience in Patients with End-Stage, Progressive Metastatic Tumors
Andreas Helisch, Clemens Kratochwil, Christian Kleist, Susanne Krämer, Juan Jose Rosales Castillo, Katharina Dendl, Hendrik Rathke, Isabelle von Goetze, Mathias Schreckenberger, Dirk Jäger, Thomas Lindner, Walter Mier, Frederik Giesel, Uwe Haberkorn, Manuel Röhrich Abstract: Radiopharmaceutical therapies (RPTs) based on fibroblast activation protein (FAP) and [...]
![Impact of fat intake on [18F]AIF-NOTA-FAPI-04 uptake in normal abdominal organs](https://sofie.com/wp-content/uploads/2024/12/thumbnail-small.jpg)
Impact of fat intake on [18F]AIF-NOTA-FAPI-04 uptake in normal abdominal organs
Jiashun Dai, Wanjing Zhou, Huaping Liu, Chengzhi Jiang, Hui Ye Abstract: Purpose: [18F]AlF-NOTA-FAPI-04 demonstrates significant physiological uptake in the gallbladder and biliary tract system, representing a limitation of this positron emission tomography (PET) tracer. The aim of this study was to evaluate the impact [...]
![Evaluation of Targeted Alpha Therapy Using [211At]FAPI1 in Triple-Negative Breast Cancer Xenograft Models](https://sofie.com/wp-content/uploads/2024/12/thumbnail-small-1.jpg)
Evaluation of Targeted Alpha Therapy Using [211At]FAPI1 in Triple-Negative Breast Cancer Xenograft Models
Kaori Abe, Tadashi Watabe, Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Yuichiro Kadonaga, Sadahiro Naka, Kazuhiro Ooe, Atsushi Toyoshima, Frederik Giesel, Takeshi Usui, Nanae Masunaga, Chieko Mishima, Masami Tsukabe, Tetsuhiro Yoshinami, Yoshiaki Sota, Tomohiro Miyake, Tomonori Tanei, Masafumi Shimoda, Kenzo Shimazu Abstract: Triple-negative breast cancer (TNBC) presents [...]