Publications
Fibroblast activation protein inhibitor-PET/CT in lung cancer: a prospective single-center study with histopathological correlation of fibroblast activation protein expression
Takashi Hiroshima, Toru Kimura, Tadashi Watabe, Takahiro Matsui, Akiisa Omura, Yusuke Sugiura, Hideki Nagata, Kenji Kimura, Eriko Fukui, Takashi Kanou, Naoko Ose, Mitsuaki Tatsumi, Frederik L Giesel, Eiichi Morii, Yasushi Shintani Background: Recent studies have demonstrated the utility of fibroblast activation protein inhibitor (FAPI)-positron emission [...]
[18F]FAPI-74 PET for Preoperative Assessment of Peritoneal Dissemination in Ovarian Cancer: A Case Series with Surgical and Histopathological Correlation
Aasa Shimizu, Tadashi Watabe, Frederik L Giesel, Yuriko Mori, Keita Asano, Yusaku Shimizu, Sadahiro Naka, Takashi Kamiya, Daisuke Katayama, Shinichiro Watanabe, Hiroki Kato, Kayako Isohashi, Mitsuaki Tatsumi, Noriyuki Tomiyama, Yasuto Kinose, Tadashi Iwamiya, Shinya Matsuzaki, Kenjiro Sawada, Michiko Kodama Background/objectives: Accurate preoperative assessment of peritoneal [...]
[68Ga]Ga-FAPI-46 PET enables non-invasive monitoring of hepatic fibrosis progression during TGF-β inhibition
Yeeun Kim, Myeongguk Jeong, Go-Eun Choi, Hyeokjin Kwon, Hyun Jin Yoon, Young-Jin Jeong, Ji Yong Park, Do-Young Kang, Sungmin Jun Abstract Hepatic fibrosis, a precursor to cirrhosis and hepatocellular carcinoma, affects millions worldwide but lacks effective therapies and depends on invasive liver biopsies for [...]
Safety of [68Ga]Ga-FAPI-46 PET/CT including hemodynamic measurements and patient-reported outcomes in cancer patients
Morten Bentestuen, Camilla Sylvest, Svend B Jensen, Lara R Soro, Aage Knudsen, Morten Ladekarl, Ole Thorlacius-Ussing, Wolfgang P Fendler, Helle D Zacho Introduction aim: Fibroblast activation protein inhibitor (FAPI) has demonstrated promising oncological diagnostic performance. Although no adverse events (AEs) have been previously reported, [...]
A 3D co-culture model with fibroblast-restricted FAP expression for cancer therapy using [212Pb]Pb-FAPI-46
Sandra K Kristiansen, Nurtene Dernjani, Øyvind S Bruland, Nina Frederike J Edin, Asta Juzeniene No Abstract Available View Publication
Ensuring enantiomeric consistency in FAPI radiopharmaceuticals
Magdalena Staniszewska, Ralph Hübner, Camilla Locatelli, Douglas Howard, Matilde Forni, Francis Man, Bent Wilhelm Schoultz, Syed Nuruddin, Ingrid Sofie Norberg-Schulz Hagen, Sherly Mosessian, Ken Herrmann, Valeska von Kiedrowski, Katharina Lückerath Abstract: Background: Enantiomeric composition may impact binding and potentially performance of a drug product but [...]





