Pipeline2022-08-11T17:06:33+00:00

Publications

Safety of [68Ga]Ga-FAPI-46 PET/CT including hemodynamic measurements and patient-reported outcomes in cancer patients

Morten Bentestuen, Camilla Sylvest, Svend B Jensen, Lara R Soro, Aage Knudsen, Morten Ladekarl, Ole Thorlacius-Ussing, Wolfgang P Fendler, Helle D Zacho Introduction aim: Fibroblast activation protein inhibitor (FAPI) has demonstrated promising oncological diagnostic performance. Although no adverse events (AEs) have been previously reported, [...]

3, May 2026|Publications|

A 3D co-culture model with fibroblast-restricted FAP expression for cancer therapy using [212Pb]Pb-FAPI-46

Sandra K Kristiansen, Nurtene Dernjani, Øyvind S Bruland, Nina Frederike J Edin, Asta Juzeniene No Abstract Available View Publication

18, Apr 2026|Publications|

Ensuring enantiomeric consistency in FAPI radiopharmaceuticals

Magdalena Staniszewska, Ralph Hübner, Camilla Locatelli, Douglas Howard, Matilde Forni, Francis Man, Bent Wilhelm Schoultz, Syed Nuruddin, Ingrid Sofie Norberg-Schulz Hagen, Sherly Mosessian, Ken Herrmann, Valeska von Kiedrowski, Katharina Lückerath Abstract: Background: Enantiomeric composition may impact binding and potentially performance of a drug product but [...]

28, Feb 2026|Publications|

90Y-FAPI-46 Radiopharmaceutical Therapy in Sarcoma and Other Solid Tumors: An Updated Cohort Analysis  

Helena Lanzafame, Ilektra A. Mavroeidi, Kim M. Pabst, Pedro Fragoso Costa, Martin Schuler, Sebastian Bauer, Jens Kurth, Martin Heuschkel, Jens T. Siveke, Ken Herrmann, Karina Kostbade, David Kersting, Stephan Leyser, Stefan Fröhling, Christoph E. Heilig, Rainer Hamacher and Wolfgang P. Fendler Abstract: Fibroblast activation [...]

13, Feb 2026|Publications|

Revealing Reliability and Practicability of FAP-RADS Version 1.0 for Structured Reporting of FAPI Imaging in Pulmonary and Urothelial Carcinoma

Emil Novruzov, Eduards Mamlins, Liam Widjaja, Sophie C Siegmund, Tadashi Watabe, Yuriko Mori, Christian Stief, Amanda Tufman, Ken Herrmann, Michael A Gorin, Martin G Pomper, Steven P Rowe, Frederik L Giesel, Rudolf A Werner, Gabriel T Sheikh Abstract: Recently, a collaborative effort among research [...]

5, Feb 2026|Publications|

Fully Automated [18F]AlF Radiolabeling Using a Microdroplet Reactor Platform

Yingqing Lu, Gitanjali Sharma, Chiara Da Pieve, Gabriela Kramer-Merek, Philip W Miller, R Michael van Dam Abstract: The preparation of 18F-labeled biomolecules for PET imaging is often challenging due to complex synthesis protocols and the short half-life of F-18 (109.8 min). The aluminum-[18F]fluoride ([18F]AlF) method [...]

15, Jan 2026|Publications|
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