Pipeline2022-08-11T17:06:33+00:00

Publications

Feasibility, Tolerability, and Preliminary Clinical Response of Fractionated Radiopharmaceutical Therapy with 213Bi-FAPI-46: Pilot Experience in Patients with End-Stage, Progressive Metastatic Tumors

Andreas Helisch, Clemens Kratochwil, Christian Kleist, Susanne Krämer, Juan Jose Rosales Castillo, Katharina Dendl, Hendrik Rathke, Isabelle von Goetze, Mathias Schreckenberger, Dirk Jäger, Thomas Lindner, Walter Mier, Frederik Giesel, Uwe Haberkorn, Manuel Röhrich Abstract: Radiopharmaceutical therapies (RPTs) based on fibroblast activation protein (FAP) and [...]

December 3rd, 2024|Publications|

Impact of fat intake on [18F]AIF-NOTA-FAPI-04 uptake in normal abdominal organs

Jiashun Dai, Wanjing Zhou, Huaping Liu, Chengzhi Jiang, Hui Ye Abstract: Purpose: [18F]AlF-NOTA-FAPI-04 demonstrates significant physiological uptake in the gallbladder and biliary tract system, representing a limitation of this positron emission tomography (PET) tracer. The aim of this study was to evaluate the impact [...]

November 7th, 2024|Publications|

Evaluation of Targeted Alpha Therapy Using [211At]FAPI1 in Triple-Negative Breast Cancer Xenograft Models

Kaori Abe, Tadashi Watabe, Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Yuichiro Kadonaga, Sadahiro Naka, Kazuhiro Ooe, Atsushi Toyoshima, Frederik Giesel, Takeshi Usui, Nanae Masunaga, Chieko Mishima, Masami Tsukabe, Tetsuhiro Yoshinami, Yoshiaki Sota, Tomohiro Miyake, Tomonori Tanei, Masafumi Shimoda, Kenzo Shimazu Abstract: Triple-negative breast cancer (TNBC) presents [...]

October 28th, 2024|Publications|

99mTc-HFAPi SPECT imaging predicts left ventricular remodeling after acute myocardial infarction

Cuncun Hua, Xiao-Ying Xi, Yeping Zhang, Ni Suo, Bin Tu, Ye Liu, Xiaoyan Yang, Xiaoyan Liu, Pixiong Su, Boqia Xie, Minfu Yang, Yanjiang Wang Abstract: Background: Despite improved treatments for acute myocardial infarction (AMI), myocardial fibrosis remains a key driver of adverse left ventricular (LV) [...]

August 4th, 2024|Publications|

Fibroblast Activation Protein-Directed Imaging Outperforms 18F-FDG PET/CT in Malignant Mesothelioma: A Prospective, Single-Center, Observational Trial

Lukas Kessler, Felix Schwaning, Martin Metzenmacher, Kim Pabst, Jens Siveke, Marija Trajkovic-Arsic, Benedikt Schaarschmidt, Marcel Wiesweg, Clemens Aigner, Till Plönes, Kaid Darwiche, Servet Bölükbas, Martin Stuschke, Lale Umutlu, Michael Nader, Dirk Theegarten, Rainer Hamacher, Wilfried E E Eberhardt, Martin Schuler, Ken Herrmann, Wolfgang P [...]

August 1st, 2024|Publications|

The Role of Fibroblast Activation Protein Inhibitor Positron Emission Tomography in Inflammatory and Infectious Diseases: An Updated Systematic Review

Domenico Albano, Alessio Rizzo, Riemer H J A Slart, Søren Hess, Edel Noriega-Álvarez, Cristina Gamila Wakfie-Corieh, Lucia Leccisotti, Andor W J M Glaudemans, Olivier Gheysens, Giorgio Treglia Abstract: The role of fibroblast activation protein inhibitor (FAPI) positron emission tomography/computed tomography (PET/CT) is emerging for [...]

May 31st, 2024|Publications|
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