Helena Lanzafame, Ilektra A. Mavroeidi, Kim M. Pabst, Pedro Fragoso Costa, Martin Schuler, Sebastian Bauer, Jens Kurth, Martin Heuschkel, Jens T. Siveke, Ken Herrmann, Karina Kostbade, David Kersting, Stephan Leyser, Stefan Fröhling, Christoph E. Heilig, Rainer Hamacher and Wolfgang P. Fendler Abstract: Fibroblast activation [...]

Emil Novruzov, Eduards Mamlins, Liam Widjaja, Sophie C Siegmund, Tadashi Watabe, Yuriko Mori, Christian Stief, Amanda Tufman, Ken Herrmann, Michael A Gorin, Martin G Pomper, Steven P Rowe, Frederik L Giesel, Rudolf A Werner, Gabriel T Sheikh Abstract: Recently, a collaborative effort among research [...]

Yingqing Lu, Gitanjali Sharma, Chiara Da Pieve, Gabriela Kramer-Merek, Philip W Miller, R Michael van Dam Abstract: The preparation of 18F-labeled biomolecules for PET imaging is often challenging due to complex synthesis protocols and the short half-life of F-18 (109.8 min). The aluminum-[18F]fluoride ([18F]AlF) method [...]

Adrien Holzgreve, Lena M Unterrainer, Kimberly Flores, Ethan C Lam, Christine E Mona, Johannes Czernin, Brian M Shuch, Anthony E Sisk Jr, Jeremie Calais Abstract: Fibroblast activation protein (FAP) has been proposed as a pan-tumor target for PET imaging using FAP-targeted tracers. Here, we [...]

William McGahan, Alexa Chadwick, Karen Lindsay, Brook Gulhane, Melissa J Latter, Thomas O'Rourke, Paul A Thomas, David Cavallucci Abstract: PET/CT using 68Ga-labeled fibroblast activation protein inhibitor (68Ga-FAPI) may detect occult metastases and identify aggressive tumor biology in patients with pancreatic ductal adenocarcinoma (PDAC). We evaluated [...]

Sajjad Sadeghpour, Atena Aghaee, Hojjat Ahmadzadehfar, Alessio Rizzo, Giorgio Treglia, Ramin Sadeghi Abstract: Background: Regarding the assessment of brain metastatic lesions, [18F]FDG PET/CT encounters challenges due to heightened physiological uptake in normal brain tissue, resulting in poor tumor-to-background ratios (TBR). Detecting brain metastases accurately has [...]