RESOURCES
Focus on FAPI Newsletter – Summer 2024
A WORD FROM OUR CHIEF SCIENTIFIC OFFICER Dear FAPI Community, I hope everyone has enjoyed their summer and found some time for rest and relaxation. We are inspired to see the conversation about FAPI’s applications continue to evolve, as reflected by its presence [...]
99mTc-HFAPi SPECT imaging predicts left ventricular remodeling after acute myocardial infarction
Cuncun Hua, Xiao-Ying Xi, Yeping Zhang, Ni Suo, Bin Tu, Ye Liu, Xiaoyan Yang, Xiaoyan Liu, Pixiong Su, Boqia Xie, Minfu Yang, Yanjiang Wang Abstract: Background: Despite improved treatments for acute myocardial infarction (AMI), myocardial fibrosis remains a key driver of adverse left ventricular (LV) [...]
Fibroblast Activation Protein-Directed Imaging Outperforms 18F-FDG PET/CT in Malignant Mesothelioma: A Prospective, Single-Center, Observational Trial GalleryFibroblast Activation Protein-Directed Imaging Outperforms 18F-FDG PET/CT in Malignant Mesothelioma: A Prospective, Single-Center, Observational Trial
Fibroblast Activation Protein-Directed Imaging Outperforms 18F-FDG PET/CT in Malignant Mesothelioma: A Prospective, Single-Center, Observational Trial
Lukas Kessler, Felix Schwaning, Martin Metzenmacher, Kim Pabst, Jens Siveke, Marija Trajkovic-Arsic, Benedikt Schaarschmidt, Marcel Wiesweg, Clemens Aigner, Till Plönes, Kaid Darwiche, Servet Bölükbas, Martin Stuschke, Lale Umutlu, Michael Nader, Dirk Theegarten, Rainer Hamacher, Wilfried E E Eberhardt, Martin Schuler, Ken Herrmann, Wolfgang P [...]
Current State of FAP Ligands for Diagnostic Use in Oncology
Presented by: Sherly Mosessian, PhD, SOFIE Chief Scientific Officer June 14, 2023 Download the Presentation
SOFIE and GE HealthCare SNMMI Symposium highlights FAP targeting
June 9, 2024 (Toronto, CA) - SNMMI annual meeting attendees had the opportunity to learn more about FAP targeting in a satellite symposium co-sponsored by SOFIE and GE HealthCare held Sunday, June 9, at the Metro Toronto Convention Center. The session, titled “Driving Molecular [...]
![[68Ga]FAPI-46 Phase 2 clinical development updates](https://sofie.com/wp-content/uploads/2024/06/FAPI_Presentation2.jpg)
[68Ga]FAPI-46 Phase 2 clinical development updates
Presented by: Sherly Mosessian, PhD, SOFIE Chief Scientific Officer 2024 Annual SNMMI Meeting – Toronto, Canada June 9, 2024 Download Presentation
Focus on FAPI Newsletter – Spring 2024
A WORD FROM OUR CHIEF SCIENTIFIC OFFICER Dear FAPI Community, SOFIE is gearing up for an exciting spring season on the FAPI front. Our Gilroy, CA, site, now joins Totowa, NJ, as a production site for GMP grade [18F]-FAPI-74 for clinical research. We [...]
The Role of Fibroblast Activation Protein Inhibitor Positron Emission Tomography in Inflammatory and Infectious Diseases: An Updated Systematic Review GalleryThe Role of Fibroblast Activation Protein Inhibitor Positron Emission Tomography in Inflammatory and Infectious Diseases: An Updated Systematic Review
The Role of Fibroblast Activation Protein Inhibitor Positron Emission Tomography in Inflammatory and Infectious Diseases: An Updated Systematic Review
Domenico Albano, Alessio Rizzo, Riemer H J A Slart, Søren Hess, Edel Noriega-Álvarez, Cristina Gamila Wakfie-Corieh, Lucia Leccisotti, Andor W J M Glaudemans, Olivier Gheysens, Giorgio Treglia Abstract: The role of fibroblast activation protein inhibitor (FAPI) positron emission tomography/computed tomography (PET/CT) is emerging for [...]
[18F]FAPI-74 serving as complementary diagnostic in Avacta Phase 1 trial
May 23, 2024 – SOFIE is pleased to partner with Avacta through Avacta’s use of [18F]FAPI-74 as a complementary diagnostic in their therapeutic studies targeting FAP. Avacta is evaluating the safety and tolerability of AVA6000, a peptide drug conjugate form of doxorubicin chemotherapy, in [...]
![[68Ga]Ga-FAPI-46 PET/CT for penile cancer - a feasibility study](https://sofie.com/wp-content/uploads/2024/06/info.ibamolecular.png)
[68Ga]Ga-FAPI-46 PET/CT for penile cancer – a feasibility study
Lennert Eismann, Stephan T Ledderose, Benazir Enzinger, Elena Berg, Thilo Westhofen, Severin Rodler, Gerald B Schulz, Johannes Toms, Adrien Holzgreve, Franz J Gildehaus, Matthias Brendel, Clemens C Cyran, Marcus Unterrainer, Christian G Stief, Peter Bartenstein, Boris Schlenker, Lena M Unterrainer Purpose: Penile cancer is a [...]