June 9, 2024 (Toronto, CA) –  SNMMI annual meeting attendees had the opportunity to learn more about FAP targeting in a satellite symposium co-sponsored by SOFIE and GE HealthCare held Sunday, June 9, at the Metro Toronto Convention Center. The session, titled “Driving Molecular Imaging Innovation with ‘FAPI’”, drew a mix of academics, industry, and other healthcare professionals for a two-hour dialogue on various aspects of FAP (fibroblast activation protein) targeting.  This marks the first year of SOFIE staging an event in partnership with GE HealthCare on FAP developments after hosting FAP-based forums at the two prior SNMMI annual meetings.  Last fall, SOFIE and GE HealthCare entered a global licensing agreement to develop and commercialize SOFIE’s two investigational products [68Ga]FAPI-46 and [18F]F-FAPI-74.

Session Co-Chairs Drs. Paul Evans (GE HealthCare) and Sherly Mosessian (SOFIE) kicked off the event that featured Dr. Andrew Scott (Olivia Newton-John Cancer Research Institute) delivering a comprehensive overview on the current state of FAP imaging in both technology and research applications.

Next, Drs. Shadi Esfahani (Massachusetts General Hospital) and Mosessian shared perspectives on the in-progress FAPI Phase II clinical studies for [18F]F-FAPI-74 and [68Ga]FAPI-46, respectively. Dr. Oliver Gheysens (Cliniques Universitaires Saint-Luc UCLouvain) offered a non-oncological viewpoint on the role of fibroblasts in inflammation and fibrosis.

After the focused talks, Dr. Scott moderated an industry-based panel on fibroblast-targeting therapeutic strategies in cancer, inflammation and fibrotic diseases. Drs. Josie Gayton (Precirix), Philippe Legenne (Molecular Partners) and Stephen Moran (Novartis) had a spirited conversation about prospective FAP therapeutic pathways that lent naturally to audience engagement with a Q&A session.

SOFIE wishes to thank GE HealthCare as a co-sponsor of this event and greatly appreciates the speakers and panelists for their expert contributions and time and effort in advancing the conversation on FAP.

To view the symposium program, click here.