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Focus on FAPI Newsletter – Fall 2025
A WORD FROM OUR CHIEF SCIENTIFIC OFFICER Dear FAPI Community, Hope everyone enjoyed a fun and relaxing summer. Our FAPI team has been very busy these last several months, and we can’t wait to share more of what’s on the horizon. It was [...]
![[68Ga]Ga-FAPI-46 PET accuracy for cancer imaging with histopathology validation: a single-centre, single-arm, interventional, phase 2 trial](https://sofie.com/wp-content/uploads/2025/09/image.png)
[68Ga]Ga-API-46 PET accuracy for cancer imaging with histopathology validation: a single-centre, single-arm, interventional, phase 2 trial
Kim M Pabst, Manuel M Weber, Christina Laschinsky, Patrick Sandach, Timo Bartel, Alina T Küper, Lukas Kessler, Marija Trajkovic-Arsic, Markus Eckstein, Elena Gilman, Michael Nader, Francesco Barbato, Lars E Podleska, Boris A Hadaschik, Rainer Hamacher, David Kersting, Nicola von Ostau, Bastian von Tresckow, Hans-Peter [...]
90 Y-FAPI-46 Theranostics Leads to Near-Complete Metabolic Response in 3 Patients with Solitary Fibrous Tumors
Helena Lanzafame, Christoph E Heilig, Eva Wardelmann, Mélanie Desaulniers, Kim Magaly Pabst, Ilektra Antonia Mavroeidi, Ina Pretzell, Pedro Fragoso Costa, Micheal Nader, Stephan Leyser, Martin Schuler, Sebastian Bauer, Jens Thomas Siveke, Leila Kamkar, Simon Kreutzfeldt, Stefan Fröhling, Sebastian Mühl, Ken Herrmann, Wolfgang Peter Fendler, [...]
Early image acquisition 68Ga-FAPI-46-PET/CT in prone position is promising in the workup of rectosigmoid and anal carcinoma
D Ufton, J Heilinger, H Weis, T Fischer, K Schomäcker, C Bruns, G Dieplinger, H Dapper, E Fokas, C Kobe, A Drzezga, S Ferdinandus, K S Roth Abstract: Purpose: To overcome difficulties with regard to anatomic discrimination of intrapelvic tumors and non-specific intrapelvic uptake (i.e. [...]
Current State of FAP Targeting Radioligands in Oncology
Presented by: Sherly Mosessian, PhD, SOFIE Chief Scientific Officer SOFIE Educational Webinar Series June 18, 2025 – Download pdf Watch Webinar
Focus on FAPI Newsletter – Spring 2025
A WORD FROM OUR CHIEF SCIENTIFIC OFFICER Dear FAPI Community, As we approach the midpoint of the year, and peak springtime here in the US, we are excited about FAPI achievements and what remains in bloom. I appreciated the opportunity to participate in [...]
Efficacy of [68Ga]Ga-FAPI-PET as a non-invasive evaluation method of liver fibrosis
Yuriko Mori, Katharina Tamburini, Emil Novruzov, Dominik Schmitt, Eleni Mavriopoulou, Sven H Loosen, Christoph Roderburg, Tadashi Watabe, Clemens Kratochwil, Manuel Röhrich, Abass Alavi, Uwe Haberkorn, Frederik L Giesel Abstract: Introduction: Liver fibrosis is a chronic fibrosing hepatic disorder following recurrent injury, characterized by the excessive [...]
![Comparison of [99mTc]Tc-FAPI SPECT/CT and [18F]FDG PET/CT as predictive biomarkers for immunotherapy response in gastrointestinal cancer](https://sofie.com/wp-content/uploads/2025/06/info.ibamolecular.jpg)
Comparison of [99mTc]Tc-FAPI SPECT/CT and [18F]FDG PET/CT as predictive biomarkers for immunotherapy response in gastrointestinal cancer
Yu Zhang, Hong Chen, Dajia Lin, Zhiyi Lin, Jiyun Shi, Hannan Gao, Chenshen Huang, Fangqing Xue, Fan Wang, Wenxin Chen Abstract: To explore the diagnostic performance of [99mTc]Tc-FAPI SPECT/CT for gastrointestinal cancer, compared to [18F]FDG PET/CT. In this analysis of a prospective trial, consecutively [...]
SOFIE Biosciences opens PET Manufacturing Facility, expanding service in Illinois, Missouri, and Indiana
Dulles, VA (March 31, 2025) – Today, SOFIE Biosciences, a leader in radiopharmaceuticals, announces the opening of a PET Manufacturing and Radiopharmacy facility in Decatur, Illinois. This site activation strengthens SOFIE’s production and distribution network, allowing the company to expand its service across Illinois, [...]
Focus on FAPI Newsletter – Winter 2025
A WORD FROM OUR CHIEF SCIENTIFIC OFFICER Dear FAPI Community, For our first newsletter of 2025, I am happy to share that things are off to a roaring start on the FAPI front. But first – a final highlight of 2024 was the [...]